VarSome NGS data analysis tools

VarSome is a genomic variant interpretation software that combines over 140 databases with a powerful variant search engine. VarSome Premium and CE‑IVD‑marked VarSome Clinical enable variant discovery, annotation, and NGS data interpretation from whole genomes, exomes, gene panels, and a wide range of sample sets.

VarSome Premium

A platform for interpretation of human genetic variants, integrating a molecular database of over 140 data sources with contributions from over 500 000 users support data from knowledge bases such as ClinVar, gnomAD, PharmGKB, OMIM, OncoKB and many more.

Built-in somatic classifiers for rapid predictions of SNVs, indels, CNVs, SVs and repeat expansions (based on AMP/ASCO/CAP guidelines).

VarSome Clinical

A CE-IVDR Class C platform for workflows in clinical genetic testing, with genetic variant calling, annotation and classification according to established guidelines.

The platform has automated variant classification and annotation, pipelines for both germline and somatic as well as dynamic and algorithmic filters.

VarSome CLinical is suitable for VCF and FASTQ files from Illumina, MGI and Element Biosciences, as well as multi-sample analysis and long read VCF files from PacBio and Oxford Nanopore.